JOMPAC
Journal of Medicine and Palliative Care

Journal of Medicine and Palliative Care (JOMPAC) is an open access scientific journal with independent, unbiased, and double-blind review under international guidelines. The purpose of JOMPAC is to contribute to the literature by publishing articles on health sciences and medicine.

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Original Article
Clinical predictors of postoperative recurrence in ovarian endometrioma: evaluation of follistatin expression
Abstract
Aims: To evaluate clinical predictors of postoperative recurrence in ovarian endometrioma and to investigate the association between epithelial follistatin immunohistochemical expression and recurrence after surgery. Methods: This retrospective study included patients who underwent surgery for ovarian endometrioma between 2008 and 2013. Demographic, clinical, and surgical data and recurrence characteristics were analyzed. Follistatin expression in endometriotic glandular epithelial cells was assessed immunohistochemically using a binary scoring system (positive vs. negative). Factors associated with recurrence were evaluated statistically. Results: Fifty patients were included, and recurrence occurred in 24 (48%). Advanced-stage disease was significantly more common in patients with recurrence (66.7% vs. 30.8%, p=0.034), and previous endometriosis surgery was markedly higher in the recurrence group (50.0% vs. 3.8%, p

Keywords : Ovarian endometrioma, endometriosis, recurrence, clinical predictors, follistatin, immunohistochemistry, fertility

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Article available in :
Volume 7, Issue 2, 2026
Page : 381-385
https://doi.org/10.47582/jompac.1899461
Article Information
Received : 28 Şub 2026
Accepted : 22 Mar 2026
Published : 27 Mar 2026
Corresponding Author :

Candost Hanedan: Department of Gynecologic Oncology, Ankara Etlik City Hospital, Ankara, Turkiye

[email protected]
Citation : Hanedan C, Kelekçi S. Clinical predictors of postoperative recurrence in ovarian endometrioma: evaluation of follistatin expression. J Med Palliat Care. 2026;7(2):381-385. doi:10.47582/jompac.1899461

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