JOMPAC
Journal of Medicine and Palliative Care

Journal of Medicine and Palliative Care (JOMPAC) is an open access scientific journal with independent, unbiased, and double-blind review under international guidelines. The purpose of JOMPAC is to contribute to the literature by publishing articles on health sciences and medicine.

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Original Article
Exploring the correlation between the fibrosis-4 score and quantitative ultrasonographic liver fat measurements in metabolic dysfunction-associated steatotic liver disease
Abstract
Aims: Metabolic dysfunction-associated steatotic liver disease (MASLD) is the most common chronic liver disease worldwide. While hepatic steatosis defines the disease, liver fibrosis is the main determinant of prognosis. The fibrosis-4 (FIB-4) score is widely used as a first-line noninvasive tool for fibrosis risk stratification, with a threshold of 1.3 recommended in clinical practice. Quantitative ultrasound techniques, including tissue attenuation imaging (TAI) and tissue scatter imaging (TSI), enable objective assessment of hepatic fat content. This study aimed to investigate the relationship between FIB-4 score and quantitative ultrasound-derived liver fat parameters in patients with MASLD. Methods: This retrospective, single-center study included 196 patients diagnosed with MASLD who underwent quantitative ultrasound liver fat assessment between January 2021 and April 2023. TAI and TSI measurements were obtained under standardized breath-hold conditions with a 1-7 MHz convex transducer. FIB-4 scores were calculated using routine laboratory parameters, and patients were categorized as FIB-4

Keywords : Metabolic dysfunction-associated steatotic liver disease, liver fibrosis, fibrosis-4 score, ultrasonography, hepatic steatosis

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Article available in :
Volume 7, Issue 2, 2026
Page : 220-224
https://doi.org/10.47582/jompac.1871085
Article Information
Received : 25 Oca 2026
Accepted : 20 Şub 2026
Published : 27 Mar 2026
Corresponding Author :

Atiye Cenay Karabörk Kılıç:

[email protected]
Citation : Karabörk Kılıç AC, Şendur HN, Aşiret E, et al. Exploring the correlation between the fibrosis-4 score and quantitative ultrasonographic liver fat measurements in metabolic dysfunction-associated steatotic liver disease. J Med Palliat Care. 2026;7(2):220-224. doi:10.47582/jompac.1871085

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