JOMPAC
Journal of Medicine and Palliative Care

Journal of Medicine and Palliative Care (JOMPAC) is an open access scientific journal with independent, unbiased, and double-blind review under international guidelines. The purpose of JOMPAC is to contribute to the literature by publishing articles on health sciences and medicine.

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Original Article
Predictive value of platelet/albumin ratio in coronary slow-flow patients
Abstract
Aims: The pathophysiology of coronary slow flow is not yet fully understood, and it is thought to be related to multiple mechanisms such as endothelial dysfunction, microvascular disorder, and atherosclerosis. In this study, we aimed to investigate the predictive value of platelet/albumin ratio (PAR) in coronary slow flow patients (CSF). In addition, we compared it with other current parameters containing albumin.
Methods: The study was designed retrospectively. The study population included a review of the medical records of 260 people who underwent coronary angiography from 2020 to 2023. The study groups consisted of 108 patients with coronary slow flow and 101 patients with normal coronary arteries who met the inclusion criteria. Various parameters such as demographic data, Platelet/Albumin Ratio and prognostic nutritional index were compared between these two groups. ROC analysis was performed on these parameters.
Results: There was no significant difference between the coronary slow flow and control groups in terms of basic demographic characteristics such as age, gender and smoking, but BMI (p<0.001), LDL (p:0.026) and total cholesterol (p:0.041) ratios were higher in the coronary slow flow group. PAR showed a significant difference between the coronary slow flow group and the control group (p:0.022). Prognostic nutritional index was not significant (p:0.142). ROC curve analysis for the PAR showed a moderate discriminatory ability with an area under the curve (ROC) of 0.592 (95% CI: 0.517-0.667). Conversely, the prognostic nutritional index exhibited limited diagnostic performance with an AUC of 0.441 (95% CI: 0.365-0.522).
Conclusion: These findings suggest that easily measurable PAR may be a valuable biomarker in assessing coronary slow flow, especially in resource-limited settings. Not only does PAR demonstrate a discriminatory ability, but it also outperforms other traditional biomarkers like the prognostic nutritional index (PNI) in this specific patient population.

Keywords : Coronary angiography, blood platelets, albumin, coronary slow flow

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Article available in :
Volume 5, Issue 6, 2024
Page : 304-308
https://doi.org/10.47582/jompac.1577163
Article Information
Received : 31 Eki 2024
Accepted : 28 Kas 2024
Published : 23 Ara 2024
Corresponding Author :

Yunus Emre Yavuz: Department of Cardiology, Faculty of Medicine, Siirt Training and Research Hospital, Siirt, Turkiye

[email protected]
Citation : Yavuz YE, Tatar S, Aslan M. Predictive value of platelet/albumin ratio in coronary slow-flow patients. J Med Palliat Care. 2024;5(6):304-308.

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