JOMPAC
Journal of Medicine and Palliative Care

Journal of Medicine and Palliative Care (JOMPAC) is an open access scientific journal with independent, unbiased, and double-blind review under international guidelines. The purpose of JOMPAC is to contribute to the literature by publishing articles on health sciences and medicine.

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Original Article
Indicators of prolonged hospital stay and rehospitalizations in hyperemesis gravidarum
Abstract
Aims: Hyperemesis gravidarum (HG) can significantly impact the quality of life of pregnant women and is the primary factor leading to hospitalization during the first half of the pregnancy. The aim of this study is to determine the ability of basic laboratory indicators that determine the severity of HG and the indices that can be calculated from them to predict the total length of hospital stay and the number of recurrent hospitalizations.
Methods: A retrospective analysis was conducted on women diagnosed with HG at a tertiary hospital from 2018 to 2021. Following the application of the inclusion criteria, we included a total of 100 eligible patients with HG (study group) and 130 healthy pregnant women (control group). Subsequently, the groups were subjected to a comparative analysis.
Results: The study group had higher levels of hemoglobin, aspartate aminotransferase (AST), alanine aminotransferase (ALT), red blood cell (RBC), white blood cells (WBC), neutrophil, mean platelet volüme (MPV), ketonuria, and lower levels of thyroid-stimulating hormone (TSH), eosinophil (p<0.005, for all). Additionally, neutrophil-to-lymphocyte ratio (NLR), systemic immune inflammation index (SII), systemic inflammatory response index (SIRI), and AST to platelet ratio index (APRI) (p<0.05, for all) were significantly higher in the study group than in the control group, but serum delta neutrophil index (DNI), platelet-to-lymphocyte ratio (PLR), monocyte-to-lymphocyte ratio (MLR) and pan-immune inflammation value (PIV) were statistically similar in both groups.
Conclusion: To the best of our knowledge, this is the first study to investigate the prediction of total hospital stay along with the number of recurrent hospitalizations with laboratory parameters in HG patients. The NLR, SII, SIRI, APRI, WBC, AST, neutrophil, and ketonuria have the potential to serve as valuable, economically viable, and readily available objective indicators for the diagnosis of HG and the prediction of recurrent hospitalization and duration of hospitalization.

Keywords : Hyperemesis gravidarum, complete blood count, ketonuria, hospitalization, predicting rehospitalization

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Article available in :
Volume 5, Issue 5, 2024
Page : 238-246
https://doi.org/10.47582/jompac.1534004
Article Information
Received : 15 Ağu 2024
Accepted : 20 Eyl 2024
Published : 26 Eki 2024
Corresponding Author :

Büşra Demir Çendek: Department of Obstetrics and Gynecology, Ankara Etlik City Hospital, Ankara, Turkiye

[email protected]
Citation : Demir Cendek B, Şeyhanlı Z, Akay A, et al. Indicators of prolonged hospital stay and rehospitalizations in hyperemesis gravidarum. J Med Palliat Care. 2024;5(5):238-246.

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