JOMPAC
Journal of Medicine and Palliative Care

Journal of Medicine and Palliative Care (JOMPAC) is an open access scientific journal with independent, unbiased, and double-blind review under international guidelines. The purpose of JOMPAC is to contribute to the literature by publishing articles on health sciences and medicine.

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Original Article
Effect of vitamin D deficiency on uric acid/HDL cholesterol ratio
Abstract
Aims: It has been suggested that vitamin D deficiency is involved in the etiology of cardiovascular diseases. High uric acid and low HDL cholesterol levels are critical risk factors for cardiovascular diseases. High uric acid levels, high total cholesterol and triglyceride levels, and low HDL-C levels are often encountered in cases with vitamin D deficiency. Our study aimed to investigate the relationship between vitamin D levels and uric acid /HDL-C (UHR) and plasma atherogenic index (PAI, triglyceride /HDL-C) in patients with vitamin D deficiency. Methods: This retrospective study included patients whose vitamin D levels were checked in our clinic. The subjects were divided into two groups according to their vitamin D levels and the relationship between laboratory variables, such as uric acid, HDL cholesterol, UHR, and plasma atherogenic index, was examined. Results: A total of 675 patients, 167 (24.7%) males and 508 (75.3%) females, were included in the study. The mean age of the patients was 53.6±15.2 years. It was found that patients with vitamin D deficiency had high UHR and PAI levels and low HDL-C levels (p=0.001, p=0.025; p=0.032, p=0.016). Conclusion Our results suggest that vitamin D deficiency has a positive correlation with HDL cholesterol levels and an impact on the risk of cardiovascular diseases by increasing the uric acid/HDL ratio and plasma atherogenic index..

Keywords : Vitamin D, uric acid/HDL cholesterol ratio, plasma atherogenic index

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Article available in :
Volume 5, Issue 3, 2024
Page : 177-181
https://doi.org/10.47582/jompac.1486189
Article Information
Received : 18 May 2024
Accepted : 19 Haz 2024
Published : 28 Haz 2024
Corresponding Author :

Ülkem Şen Uzeli: Department of Internal Medicine, Hitit University Erol Olçok Training and Research Hospital, Çorum, Turkiye

[email protected]
Citation : Şen Uzeli Ü, Doğan AG. Effect of vitamin D deficiency on uric acid/HDL cholesterol ratio. J Med Palliat Care. 2024;5(3):177- 181.

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