JOMPAC
Journal of Medicine and Palliative Care

Journal of Medicine and Palliative Care (JOMPAC) is an open access scientific journal with independent, unbiased, and double-blind review under international guidelines. The purpose of JOMPAC is to contribute to the literature by publishing articles on health sciences and medicine.

eISSN: 2717-7505
Creative Commons CC BY-NC-ND 4.0 International License.
EndNote Style

Submit Manuscript

Index
Original Article
The characteristics of patients undergoing endobronchial ultrasonography-guided transbronchial needle aspiration (EBUS-TBNA): single-center experience
Abstract
Aims: We aimed to present the features of our Endobronchial ultrasonography-guided transbronchial needle aspiration (EBUS-TBNA) cases, the lymph nodes that were biopsied, their pathological diagnoses, and the complications that developed due to the procedure.
Methods: All cases who underwent EBUS-TBNA between January 2016 and December 2023 in the chest diseases clinic of a training and research hospital were retrospectively screened. The patients who underwent the procedure (n=274) were included in the study. Cases in which fine needle aspiration biopsy was performed with EBUS-TBNA and the material obtained was not diagnostic (n=3) or in which the pathology result could not be obtained in the files (n=9) were excluded from the study. The design of our study was cross-sectional and planned as a descriptive study.
Results: Of the 262 patients included in the analysis, 66.4% (n=174) were male and the average age of the population was 60.8±11.4 years. When EBUS-TBNA indications were evaluated, the procedure was performed for diagnostic purposes in 96.9% (n=254) and for re-evaluation after chemotherapy in 3.1%. EBUS-TBNA procedure was performed in 16.8% (n=44) patients due to mediastinal mass and in 83.2% (n=218) patients due to mediastinal lymphadenopathy. The most common stations where biopsy is performed with the EBUS-TBNA process are the subcarinal (7) and lower right paratracheal (4R) lymph node stations. When the biopsy results were evaluated, malignancy was reported in 54.6% (n=143) of the patients. The complications related to the EBUS-TBNA procedure were generally mild and trancient .
Conclusion: EBUS-TBNA is a minimally invasive method used in the diagnosis and staging of lung cancer, the evaluation of non-endobronchial lesions, the diagnosis of benign diseases of the mediastinum, and the diagnosis of mediastinal metastases of extrathoracic malignancies. In experienced centers like our clinic, the diagnostic value of the procedure is high and the complication rates are very low.

Keywords : EBUS, lung cancer, metastasis

Download Article


1. De Leyn P, Dooms C, Kuzdzal J, et al. Revised ESTS guidelines for preoperative mediastinal lymph node staging for non-small-cell lung cancer. <em>Eur J Cardiothorac Surg</em>. 2014;45(5):787-798.
2. Murthi M, Donna E, Arias S, et al. Diagnostic accuracy of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) in real life. <em>Front Med (Lausanne)</em>. 2020;7:118.
3. Wahidi MM, Herth F, Yasufuku K, et al. Technical aspects of endobronchial ultrasound-guided transbronchial needle aspiration: CHEST guideline and expert panel report. <em>Chest.</em> 2016;149(3):816-835.
4. Muriana P, Rossetti F. The role of EBUS-TBNA in lung cancer restaging and mutation analysis. <em>Mediastinum</em>. 2020;30(4):23.
5. Yamamoto S, Nakayama M. Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA): revolutionizing the landscape of lung disease diagnostics. <em>J Med Ultrason (2001)</em>. 2024;51(2):245-251. doi: 10.1007/s10396-023-01391-y
6. Leiter A, Veluswamy RR, Wisnivesky JP. The global burden of lung cancer: current status and future trends. <em>Nat Rev Clin Oncol</em>. 2023;20(9):624-639.
7. Torre M, Reda M, Musso V, Danuzzo F, Mohamed S, Conforti S. Diagnostic accuracy of endobronchial ultrasound-transbronchial needle aspiration (EBUS-TBNA) for mediastinal lymph node staging of lung cancer. <em>Mediastinum</em>. 2021:25(5):15.
8. Yılmaz MU, Erol S, Ermete S, et al. Endobronşial ultrason-transbronşial iğne aspirasyonu; &ouml;<span dir="RTL">ğ</span>renme d&ouml;nemi sonu&ccedil;ları. <em><span dir="RTL">İ</span></em><em>zmir</em> <em>G&ouml;ğ Hast Derg</em>. 2015;29(1):15-20.
9. &Ouml;zt&uuml;rk A, &Ccedil;i&ccedil;ek T, Yılmaz A. What is the yield of EBUS-TBNA for re-evaluation of previously treated non-small-cell lung cancer? <em>Turk J Med Sci</em>. 2023;53(2):586-593.
10. Batum &Ouml;, Katgı N, &Ouml;zdemir &Ouml;, Yılmaz U. Diagnostic efficacy of EBUS-TBNA in benign diseases in a population with a high prevalence of tuberculosis. <em>Diagn Cytopathol</em>. 2021;49(3):374-380.
11. Ortakoylu MG, Iliaz S, Bahadir A, et al. Diagnostic value of endobronchial ultrasound-guided transbronchial needle aspiration in various lung diseases. <em>J Bras Pneumol</em>. 2015; 41(5):410-414.
12. Demird&ouml;ğen E, Ursavaş A, Aydın G&uuml;&ccedil;l&uuml; &Ouml;, Acet &Ouml;zt&uuml;rk NA, &Ouml;zkaya G, Karadağ M. Diagnostic performance of EBUS-TBNA and its interrelation with PET-CT in patients with extra-thoracic malignancies. <em>Tuberk Toraks.</em> 2020;68(3):285-292.
13. Tertemiz KC, Alpaydin AO, Karacam V. The role of endobronchial ultrasonography for mediastinal lymphadenopathy in cases with extrathoracic malignancy. <em>Surg Endosc</em>. 2017;31(7):2829-2836.
14. Fournier C, Hermant C, Gounant V, et al. Diagnostic of mediastinal lymphadenopathy in extrathoracic cancer: a place for EBUS-TBNA in real life practice? <em>Respir Med Res</em>. 2019;75:1-4.
15. Navani N, Nankivell M, Woolhouse I, et al. Endobronchial ultrasound-guided transbronchial needle aspiration for the diagnosis of intrathoracic lymphadenopathy in patients with extrathoracic malignancy: a multicenter study. <em>J Thorac Oncol</em>. 2011;6(9):1505-1509.
16. Sanz-Santos J, Cirauqui B, Sanchez E, et al. Endobronchial ultrasound-guided transbronchial needle aspiration in the diagnosis of intrathoracic lymph node metastases from extrathoracic malignancies. <em>Clin Exp Metastasis</em>. 2013;30(4):521-528.
17. <span dir="RTL">Ş</span>ent&uuml;rk A, &Ccedil;elik D, Aksoy Altınboğa A. Rapid on-site evaluation (ROSE) during endobronchial ultrasound bronchoscopy (EBUS) in the diagnosis of granulomatous diseases. <em>Int J Clin Pract</em>. 2021;75(12):e15002. doi: 10.1111/ijcp.15002
18. Gu P, Zhao YZ, Jiang LY, Zhang W, Xin Y, Han BH. Endobronchial ultrasound-guided transbronchial needle aspiration for staging of lung cancer: a systematic review and meta-analysis. <em>Eur J Cancer</em>. 2009;45(8):1389-1396.
19. &Ccedil;a<span dir="RTL">ğ</span>layan B, Yılmaz A, Bila&ccedil;eroğlu S, C&ouml;mert S<span dir="RTL">Ş</span><span dir="RTL">, </span>Demirci NY, Salep&ccedil;i B. Complications of convex-probe endobronchial ultrasound-guided transbronchial needle aspiration: a multi-center retrospective study. <em>Respir Care</em>. 2016;61(2):243-248.
Article available in :
Volume 5, Issue 3, 2024
Page : 155-159
https://doi.org/10.47582/jompac.1473255
Article Information
Received : 25 Nis 2024
Accepted : 19 May 2024
Published : 28 Haz 2024
Corresponding Author :

Savaş Gegin: Department of Chest Diseases, Samsun Training and Research Hospital, Samsun, Turkiye

[email protected]
Citation : Gegin S, Özdemir B, Arslan Aksu, Yazıcıoğlu İM, Özdemir L.The characteristics of patients undergoing endobronchial ultrasonography-guided transbronchial needle aspiration (EBUS-TBNA): single-center experience. J Med Palliat Care. 2024;5(3):155-159.

Read: 438
Cited: 0
Download : 78
_Footer