JOMPAC
Journal of Medicine and Palliative Care

Journal of Medicine and Palliative Care (JOMPAC) is an open access scientific journal with independent, unbiased, and double-blind review under international guidelines. The purpose of JOMPAC is to contribute to the literature by publishing articles on health sciences and medicine.

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Acute fibrinous and organizing pneumonia
Abstract
Acute fibrinous and organizing pneumonia (AFOP), first described histologically by Beasley et al.1 in 2002. AFOP occurs in a wide age range (38-78 age) and in a non-sexist spectrum of patients. Although idiopathic cases have been reported, case series in which the underlying etiology is known. The histologically specific pattern is the presence of organized intra-alveolar fibrin and is the essential parameter for diagnosis. There is no significant difference in the radiological pattern except for the halo finding in the comparison of AFOP and COP. In patients presenting with an acute and more fulminant picture, the clinic presents with rapidly worsening respiratory failure. The main complaints were fever, cough and chest pain respectively. Since AFOP is a diagnosis of exclusion, most patients are diagnosed with pneumonia that does not respond to treatment or has delayed resolution during follow up. Although the clinical presentations of the fulminant and subacute forms of AFOP are different, a clear distinction cannot be made for treatment due to the high mortality of the fulminant form. The prognosis is poor in acute fulminant cases.

Keywords : Organized pneumonia, interstitial lung disease, acute acute fibrinous

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1. Beasley MB, Franks TJ, Galvin JR, Gochuico B, Travis WD. Acute fibrinous and organizing pneumonia a histologic pattern of lung injury and possible variant of diffuse alveolar damage. Arch Pathol Laborat Med.2002;126(9):1064-1070.
2. Raghu G, Remy-Jardin M, Richeldi L, et al. Idiopathic pulmonary fibrosis (an update) and progressive pulmonary fibrosis in adults: an official ATS/ERS/JRS/ALAT clinical practice guideline. Am J Respir Crit Care Med. 2022;205(9):e18-e47.
3. Wang Y, Li Y, Wang Q, et al. Acute fibrinous and organizing pneumonia; a case report. Medicine. 2019;98(8):e14537.
4. Onishi Y, Kawamura T, Higashino T, Mimura R, Tsukamoto H, Sasaki S. Clinical features of acute fibrinous and organizing pneumonia: an early histologic pattern of various acute inflammatory lung diseases. PLoS One. 2021;16(4):e0249300.
5. Gomes R, Padrão E, Dabó H, et al. Acute fibrinous and organizing pneumonia: a report of 13 cases in a tertiary university hospital. Medicine. 2016;95(27):e4073.
6. Simmons GL, Chung HM, McCarty JM, et al. Treatment of acute fibrinous organizing pneumonia following hematopoietic cell transplantation with etanercept. Bone Marrow Transplant. 2017;52(1):141-143.
7. Kumar S, Mishra M, Goyal K, Bhatt R, Joshi P, Bansal S. Acute fibrinous organizing pneumonia: a rare lung pathology. Monaldi Arch Chest Dis. 2019;89(2):1016.
8. Ford D, Charoenpong P, Boparai S. Acute fibrinous organizing pneumonia: a new association. Chest. 2021;160(4):A1654.
9. Kuza C, Matheos T, Kathman D, Heard SO. Life after acute fibrinous and organizing pneumonia: a case report of a patient 30 months after diagnosis and review of the literature. J Crit Care. 2016;31(1):255-261.
10. Damas C, Morais A, Moura CS, Marques JA. Acute fibrinous and organizing pneumonia. Pulmonol. 2006;12(5):615-620.
11. Lu J, Yin Q, Zha Y, et al. Acute fibrinous and organizing pneumonia: two case reports and literature review. BMC Pulm Med. 2019;19(1):141.
12. Onishi Y, Kawamura T, Nakahara Y, et al. Factors associated with the relapse of cryptogenic and secondary organizing pneumonia. Respir Investig 2017;55(1):10-15.
13. Sauter JL, Butnor KJ. Expanding the spectrum of pulmonary histopathological manifestations of antisynthetase syndrome: anti-EJ-associated acute fibrinous and organizing pneumonia. Histopathol. 2014;65(4):581-582.
14. Ning YJ, Ding PS, Ke ZY, Zhang YB, Liu RY. Successful steroid treatment for acute fibrinous and organizing pneumonia: a case report. World J Clin Cases. 2018;6(15):1053-1058.
Article available in :
Volume 5, Issue 2, 2024
Page : 144-146
https://doi.org/10.47582/jompac.1460019
Article Information
Received : 27 Mar 2024
Accepted : 25 Nis 2024
Published : 30 Nis 2024
Corresponding Author :

Berna Akıncı Özyürek: Department of Chest Disease, Ankara Atatürk Sanatorium Training and Research Hospital, University of Health Sciences, Ankara, Turkiye

[email protected]
Citation : Ensarioğlu K, Akıncı Özyürek B. Acute fibrinous and organizing pneumonia. J Med Palliat Care. 2024;5(2):144-146.

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