JOMPAC
Journal of Medicine and Palliative Care

Journal of Medicine and Palliative Care (JOMPAC) is an open access scientific journal with independent, unbiased, and double-blind review under international guidelines. The purpose of JOMPAC is to contribute to the literature by publishing articles on health sciences and medicine.

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Original Article
Persistent iatrogenic atrial septal defect after cryoballoon ablation for atrial fibrillation
Abstract
Aims: Pulmonary vein isolation (PVI) by cryoballoon ablation (CB) technology is effective and safe treatment option for atrial fibrillation (AF). CB is performed by large diameter, 15Fr (4.95mm) transseptal sheath that may lead to creation of iatrogenic atrial septal defect (iASD). The objective of this study was to assess the incidence of iASD in patients who had undergone CB.
Methods: Patients with AF having undergone Arctic Front® CB ablation and a subsequent transesophageal echocardiography (TEE) examination during post-ablation follow up period were consecutively enrolled. During all CB procedures, 15Fr transseptal sheath (Flex Cath, Medtronic, Minneapolis, MN) was utilized via single transseptal puncture (TsP).
Results: Twenty-eight patients (15 females, mean age 55.8+15.5) with paroxysmal (n=24) or persistent (n=4) AF formed study group. iASD was present 11 (39.3%) of them after mean follow-up time of 17.3+6.2 months. The procedural time is significantly longer in patient with iASD (119.0+8.8 minutes, p=0.01). No patients died or suffered from any clinically significant cerebral ischemic event. There was no sign of increase in systolic pulmonary arterial pressure (sPAP).
Conclusion: iASD after CB was found to be present in 39.3% of patient during a mean follow-up time of 17.3+6.2 months. The prolonged CB procedural time was the only factor that predicted iASD in our study. No adverse clinic events that might be related to iASD was observed during follow-up period.

Keywords : Iatrogenic atrial septal defect, cryoballoon ablation, pulmonary vein isolation, atrial fibrillation

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Article available in :
Volume 5, Issue 2, 2024
Page : 118-123
https://doi.org/10.47582/jompac.1446976
Article Information
Received : 04 Mar 2024
Accepted : 22 Nis 2024
Published : 30 Nis 2024
Corresponding Author :

Görkem Yıldız: Department of Cardiology, Faculty of Medicine, Yüksek İhtisas University, Ankara, Turkiye

[email protected]
Citation : Yıldız G, Candemir B, Gerede Uludağ DM. Persistent iatrogenic atrial septal defect after cryoballoon ablation for atrial fibrillation. J Med Palliat Care. 2024;5(2):118-123.

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