JOMPAC
Journal of Medicine and Palliative Care

Journal of Medicine and Palliative Care (JOMPAC) is an open access scientific journal with independent, unbiased, and double-blind review under international guidelines. The purpose of JOMPAC is to contribute to the literature by publishing articles on health sciences and medicine.

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Original Article
Predictive factors for acute pancreatic and peripancreatic fluid development in patients with acute pancreatitis
Abstract
Aims: Acute fluid collections after acute pancreatitis carries risk of serious complications as infected pseudocyst and Wall off Necrose development. Hence, it is important to predict the development of acute fluid collections for treatment and management of acute pancreatitis. In this study, it is aimed to investigate predictive factors for development of acute fluid collections in patients with acute pancreatitis.
Methods: Total of 438 patients diagnosed with acute pancreatitis were screened. According to the Revised Atlanta Classification fluid development after acute pancreatitis was determined and the relationship between fluid development and the hematological/biochemical parameters of the patients at the time of admission was investigated. The best cut-off point of laboratory measurements for fluid development was determined by ROC analysis and the factors that may be most decisive in distinguishing between the patients with and without fluid development were determined by multivariate forward stepwise logistic regression analysis.
Results: It is found that developing acute fluid collections after acute pancreatitis was higher in patients with younger age and male gender. Also the risk of developing acute fluid collections after acute pancreatitis was found to be 6.2 times higher in patients with CRP/Albumin ratio greater than 1.09; 2.5 times higher in patients with ALP below 199.5 U/L; 1.9 times higher in patients with WBC greater than 11,6 ×10?/L and 1.5 times higher in patients with PLR above 197.1. Also the risk of developing acute necrotic collections after acute pancreatitis was 3 times higher in patients with serum calcium level below 8,6 mg/dl.
Conclusion: It has been determined that, presence of high CRP/albumin ratio, high NLR and low serum ALP level can be used as an indicator in predicting acute pancreatic and peripancreatic fluid development.

Keywords : Acute fluid collections, acute necrotic collection, acute pancreatitis, acute peripancreatic fluid collections

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Article available in :
Volume 4, Issue 6, 2023
Page : 630-636
https://doi.org/10.47582/jompac.1392853
Article Information
Received : 18 Kas 2023
Accepted : 06 Ara 2023
Published : 31 Ara 2023
Corresponding Author :

Mehmet Veysel Coşkun: Department of Internal Medicine, Sivrihisar City Hospital, Eskişehir, Turkey

[email protected]
Citation : Coşkun MV, Karaahmetoğlu S, İnan O, Kurtipek AC. Predictive factors for acute pancreatic and peripancreatic fluid development in patients with acute pancreatitis. J Med Palliat Care. 2023;4(6):630-636.

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