JOMPAC
Journal of Medicine and Palliative Care

Journal of Medicine and Palliative Care (JOMPAC) is an open access scientific journal with independent, unbiased, and double-blind review under international guidelines. The purpose of JOMPAC is to contribute to the literature by publishing articles on health sciences and medicine.

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Original Article
Intensive care unit: mortality score in early prediction of mortality in critical COVID-19 patients
Abstract
Aims: The mortality data available in the literature with regard to patients with SARS-COV-2, thus requiring hospitalization in the intensive care unit (ICU) are not sufficient. This research aims to compare the correlation between COVID-19 mortality ratios (CMR), AST/ALT and neutrophil/lymphocyte (N/L) ratios of non-smoker COVID-19 patients hospitalized in the ICU and their mortality rates. Methods: This cross-sectional study was conducted on 77 patients hospitalized in the ICU. Female participants constituted 64.9% (n=50) of the study group while male made up 35.1% (n=27); the mean age was 61.3±14.3 and 66.2% (n=51) of the patients died. To exclude the adverse effect of smoking on mortality, patients were confirmed to be non-smokers by analyzing the cotinine levels in urine samples. For this purpose, patients’ age, gender, comorbidities, fever, pulse, blood pressure, saturation values, APACHE scores and biochemical parameters were evaluated. Results: In the study, 66.2% (n=51) of the patients died during follow-up. Age, urea, creatinine, AST/ALT, N/L ratio and CMR values of the nonsurvivors were significantly higher than those of the survivors. The systolic blood pressure and lymphocyte values of non-survivors were lower than survivors. Conclusions: The conclusion of the study revealed that CMR scores, AST/ALT levels and the N/L ratio can effectively be utilized in early period to project the mortality rates of non (active) smoking patients with critical COVID-19 infection hospitalized in the ICU.

Keywords : Keywords: SARS-COV-2, intensive care unit, COVID-19 mortality ratio; cotinine; smokers and non-smokers

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Article available in :
Volume 4, Issue 5, 2023
Page : 572-578
https://doi.org/10.47582/jompac.1346978
Article Information
Received : 21 Ağu 2023
Accepted : 14 Eki 2023
Published : 27 Eki 2023
Corresponding Author :

Emel Sağlam: Department of Internal Medicine, Bağcılar Training and Research Hospital, İstanbul, Turkey

[email protected]
Citation : Sağlam E, Savaş A, Oke D, Özlü C, Koçar B, Erkalp K. Intensive care unit: mortality score in early prediction of mortality in critical COVID-19 patients. J Med Palliat Care. 2023;4(5):572-578.

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