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EndNote Style
Original Article
The role of the systemic inflammatory response index (SIRI) in the prediction of chronic total occlusion: useful or not?
Aims: Inflammation is very important in the pathogenesis of atherosclerosis and coronary artery disease (CAD). Chronic total occlusion (CTO) is a chronic form of CAD and is common in patients with severe CAD. The aim of this study was to determine the association of the systemic inflammatory response index (SIRI), a marker of inflammation, with CTO.
Methods: Our study was retrospective and included 100 CAD patients with CTO and 100 CAD patients without CTO. SIRI was compared between the two groups.
Results: Among the basic clinical and laboratory characteristics of the patients, age, white blood cell, and neutrophil counts were statistically higher in the CTO group (p=0.044, p=0.044, p=0.036, respectively). SIRI parameters were similar between the groups, and no statistical difference was observed (p=0.111). According to the ROC analysis, the optimum cut-off value for SIRI was >1040 (sensitivity 70.0% and specificity 44.0%).
Conclusion: SIRI is not a useful predictor for the detection of CTO.

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Volume 4, Issue 5, 2023
Page : 542-546