JOMPAC
Journal of Medicine and Palliative Care

Journal of Medicine and Palliative Care (JOMPAC) is an open access scientific journal with independent, unbiased, and double-blind review under international guidelines. The purpose of JOMPAC is to contribute to the literature by publishing articles on health sciences and medicine.

eISSN: 2717-7505
Creative Commons CC BY-NC-ND 4.0 International License.
EndNote Style

Submit Manuscript

Index
Original Article
Prenatal diagnosis and clinical outcomes of isolated interruption of the inferior vena cava: an analysis of 12 cases
Abstract
Aims: This study aimed to thoroughly examine the clinical presentations and outcomes associated with prenatally detected isolated interrupted inferior vena cava (IIVC) with azygos continuation. The intention was to provide further insight into the importance of prenatal diagnosis for this particular condition.
Methods: A longitudinal study was conducted on a cohort of 12 fetuses who had been diagnosed prenatally with inferior vena cava interruption and azygos vein continuation. Comprehensive fetal anomaly scans and echocardiography were performed, and pediatric cardiologists further validated postnatal diagnoses. In addition, genetic testing and comprehensive follow-up procedures were implemented.
Results: The research findings substantiated the considerable diagnostic precision of prenatal identification, as evidenced by the 100% confirmation rate in postnatal assessments. Most patients demonstrated positive outcomes, underscoring the significance of prenatal diagnosis. Genetic testing results indicated that all the studied cases exhibited normal chromosomal configurations.
Conclusion: This study contributes to understanding this rare vascular anomaly and its implications in clinical practice. Additionally, our findings emphasize the importance of regular prenatal screenings and the need for healthcare providers to be knowledgeable about isolated IIVC cases. By increasing awareness and understanding of this vascular anomaly, healthcare professionals can provide better care and support for affected patients and their families. Furthermore, future research should investigate the potential genetic factors contributing to the development of isolated IIVC, which could further enhance our understanding of this condition.

Keywords : Isolated interruption inferior vena cava, azygos continuation, prenatal diagnosis, echocardiography

Download Article


1. Giang DTC, Rajeesh G, Vaidyanathan B. Prenatal diagnosis ofisolated interrupted inferior vena cava with azygos continuationto superior vena cava. Ann Pediatr Cardiol. 2014;7:49-51.
2. Bass JE, Redwine MD, Kramer LA, Huynh PT, Harris JHJ.Spectrum of congenital anomalies of the inferior vena cava:cross-sectional imaging findings. Radiographics. 2000;20(3):639-652.
3. Celentano C, Malinger G, Rotmensch S, Gerboni S, Wolman Y,Glezerman M. Prenatal diagnosis of interrupted inferior venacava as an isolated finding: a benign vascular malformation.Ultrasound Obstet Gynecol. 1999;14(3):215-218.
4. Tubau A, Grau J, Filgueira A, et al. Prenatal and postnatalimaging in isolated interruption of the inferior vena cava withazygos continuation. Prenat Diagn. 2006;26:872-874.
5. Bronshtein M, Khatib N, Blumenfeld Z. Prenatal diagnosis andoutcome of isolated interrupted inferior vena cava. Am J ObstetGynecol. 2010;202(4):398.e1-4.
6. Shahrouki P, Lee EW, Ruehm S. Polysplenia syndrome and sicklecell trait: extensive deep venous thrombosis from venous stasisand hypercoagulability. Clin Imaging. 2022;82:127-131.
7. Xu Q, Sun HX, Xie JS, Wang JL, Pei QY, Zhang XH. Characteristicsand prognosis of interrupted inferior vena cava with azygouscontinuation. Zhonghua Fu Chan Ke Za Zhi. 2018;53(3):149-154.
8. Vijayaraghavan SB, Raja V, Chitra T V. Interrupted inferiorvena cava and left-sided subrenal inferior vena cava: prenataldiagnosis. J Ultrasound Med. 2003;22(7):747-752.
9. Moradi B, Moosavi NS, Kazemi MA, Tahmasebpour AR, FattahiMasrour F. A case of prenatally detected left isomerism andhemiazygos continuation of inferior vena cava. J Clin Ultrasound.2017;45(7):430-433.
10. Sheley RC, Nyberg DA, Kapur R. Azygous continuation of theinterrupted inferior vena cava: a clue to prenatal diagnosis of thecardiosplenic syndromes. J Ultrasound Med. 1995;14(5):381-387.
11. Babaoğlu K, Doğan Y, Başar EZ, Usta E. Prenatal diagnosisof hepatic interruption of the inferior vena cava with azygos/hemiazygos continuation without structural heart defects: a caseseries. J Clin Ultrasound. 2022;50(6):795-802.
12. Effler DB, Greer AE, Sifers EC. Anomaly of the vena cava inferior;report of fatality after ligation. JAMA. 1951;146(14):1321-1322.
13. Mandato Y, Pecoraro C, Gagliardi G, Tecame M. Azygos andhemiazygos continuation: an occasional finding in emergencydepartment. Radiol Case Rep. 2019;14(9):1063-1068.
14. Lambert M, Marboeuf P, Midulla M, et al. Inferior vena cavaagenesis and deep vein thrombosis: 10 patients and review of theliterature. Vasc Med. 2010;15(6):451-459.
15. Kwan KJ, Li H-L, Chan YC, Huang J-X, Cui D-Z, Cheng SW.Venous thromboembolism in a patient with ınterrupted ınferiorvena cava and compressed azygos continuation: a case report andreview of literature. Vasc Endovascular Surg. 2023;57(6):643-649.
16. Pasqui E, de Donato G, Camarri S, et al. Case report: inferior venacava agenesia in a young male patient presenting with bilateraliliac veins thrombosis. Front Surg. 2022;9:832336.
17. Thomas SD, Ofri A, Tang T, Englund R. Endovascularreconstruction of an interrupted inferior vena cava. Int J SurgCase Rep. 2014;5(2):59-62.
18. Raymundo SRO, Cabral VS, Cavalieri RF, Reis Neto F.Thrombolysis for deep venous thrombosis associated withinferior vena cava agenesis in a young patient. BMJ Case Rep.2019;12(5):e229840.
19. Sagban TA, Grotemeyer D, Balzer KM, et al. Surgical treatmentfor agenesis of the vena cava: a single-centre experience in 15cases. Eur J Vasc Endovasc Surg. 2010;40(2):241-245.
20. Parsa P, Lane JS 3rd, Barleben AR, Owens EL, Bandyk D.Congenital agenesis of inferior vena cava: a rare cause ofunprovoked deep venous thrombosis. Ann Vasc Surg. 2015;29(5).
Article available in :
Volume 4, Issue 5, 2023
Page : 530-534
https://doi.org/10.47582/jompac.1358089
Article Information
Received : 10 Eyl 2023
Accepted : 03 Eki 2023
Published : 27 Eki 2023
Corresponding Author :

Işıl Turan Bakırcı: Division of Perinatology, Department of Obstetrics and Gynecology, Başakşehir Çam and Sakura City Hospital, İstanbul, Turkey

[email protected]
Citation : Acar Z, Turan Bakırcı I, Acar DK, Bornaun H. Prenatal diagnosis and clinical outcomes of isolated interruption of the inferior vena cava: an analysis of 12 cases. J Med Palliat Care. 2023;4(5):530-534.

Read: 41
Cited: 0
Download : 84
_Footer