JOMPAC
Journal of Medicine and Palliative Care

Journal of Medicine and Palliative Care (JOMPAC) is an open access scientific journal with independent, unbiased, and double-blind review under international guidelines. The purpose of JOMPAC is to contribute to the literature by publishing articles on health sciences and medicine.

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Original Article
Evaluation of endothelial dysfunction and inflammation in recovered COVID-19 patients
Abstract
Aims: In our study, we aimed to evaluate the endothelial functions and hemogram parameters, which are considered as inflammation markers, in young people with a history of COVID-19 infection.
Methods: This prospective study included 109 recovered COVID-19 patients and 50 healthy controls. Demographic characteristics, laboratory values and flow-mediated vasodilation test (FMD) results of the groups were compared.
Results: Demographic and biochemistry parameters of the groups were similar. The calculated FMD values were significantly lower in the recovered COVID-19 patient group compared to the control group (8.66±3.31 vs 11.69±3.01; p=0.001). While there was no difference between the groups in terms of neutrophil/lymphocyte ratio (NLR) and Platelet/Lymphocyte ratio (PLR), systemic immune-inflammation index (SII) was found to be higher in the patient group with recovered COVID-19 patients (p=0.02). In correlation analysis, there was a low moderate negative correlation between FMD and SII (r=-0.35, p=0.002).
Conclusion: FMD measurement and SII are simple, easily accessible parameters that can be useful in the early period to evaluate cardiovascular risks in the long term after COVID-19. There is a need for larger and multicenter studies on this subject.

Keywords : Endothelial dysfunction, COVID-19, inflammation.

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Article available in :
Volume 4, Issue 5, 2023
Page : 511-515
https://doi.org/10.47582/jompac.1344838
Article Information
Received : 17 Ağu 2023
Accepted : 27 Eyl 2023
Published : 27 Eki 2023
Corresponding Author :

Yasemin Doğan: Department of Cardiology, Kayseri City Hospital, Kayseri, Turkey

[email protected]
Citation : Doğan Y, Turunç Özdemir A. Evaluation of endothelial dysfunction and inflammation in recovered COVID-19 patients. J Med Palliat Care. 2023;4(5):511-515.

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