JOMPAC
Journal of Medicine and Palliative Care

Journal of Medicine and Palliative Care (JOMPAC) is an open access scientific journal with independent, unbiased, and double-blind review under international guidelines. The purpose of JOMPAC is to contribute to the literature by publishing articles on health sciences and medicine.

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Original Article
Colonoscopic evaluation of acromegalic patients: a single center experience
Abstract
Aims: To investigate the importance and necessity of colonoscopic screening in patients with acromegaly.
Methods: This study included 82 patients with acromegaly and, 82 healthy individuals as the control group who underwent screening colonoscopy in the Gastroenterology Department of Karadeniz Technical University, between January 2008-January 2021.
Results: The mean age of the patients was 45.71±12.61 years at the time of acromegaly diagnosis. 51.2% (n=42) of patients were female. Abnormal findings including evidence of polyps, and inadequate bowel preparation were significantly more common in the acromegaly group than the control(p<0,05). The a growth hormone (GH) level measured at the time of diagnosis was significantly higher in patients with acromegaly diagnosed with inadequate bowel preparation (p<0,05). There was no significant difference between the two groups in non-polyp colonoscopy findings, polyp localization, histologic types and colorectal cancer.
Conclusion: The frequency of polyps is higher in patients with acromegaly than in the normal population and therefore colonoscopy screening should be performed. It would be reasonable to perform bowel preparation in patients with acromegaly (especially those with high GH at the time of diagnosis) using an approach different from standard bowel preparation, as the rate of inadequate bowel preparation is higher in this group of patients.

Keywords : Acromegaly, colonoscopy, growth hormone, colon polyps

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Article available in :
Volume 4, Issue 5, 2023
Page : 395-399
https://doi.org/10.47582/jompac.1345430
Article Information
Received : 18 Ağu 2023
Accepted : 04 Eyl 2023
Published : 27 Eki 2023
Corresponding Author :

Yasemin Emür Günay: Department of Endocrinology and Metabolism, Giresun Training and Research Hospital, Giresun, Turkey

[email protected]
Citation : Emür Günay Y, Durak S, Coşar AM, Erkut B, Fidan S. Colonoscopic evaluation of acromegalic patients: a single center experience. J Med Palliat Care. 2023;4(5):395-399.

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