JOMPAC
Journal of Medicine and Palliative Care

Journal of Medicine and Palliative Care (JOMPAC) is an open access scientific journal with independent, unbiased, and double-blind review under international guidelines. The purpose of JOMPAC is to contribute to the literature by publishing articles on health sciences and medicine.

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Original Article
The clinical course of COVID-19 in pregnant and non-pregnant women
Abstract
Aims: Pregnancy is a physiological condition that predisposes women to respiratory complications of viral infections thus, bringing the risk of developing more severe disease. The aim of this research was to elucidate the clinical course of COVID-19 in pregnant and non-pregnant women of childbearing age. Mortality rate, laboratory parameters, the occurence of cytokine storm in both groups and the response to treatment have been investigated.
Methods: A total of 88 women of childbearing age with a diagnosis of COVID-19 disease has been retrospectively analyzed. Age, comorbidity, length of stay in the intensive care unit and treatment regimen of patients have been obtained from hospital database. Ferritin, IL-6, CRP, procalcitonin, D-dimer, urea, creatinine, GFR, ALT, AST, LDH, lymphocyte count, neutrophil count, white blood cell count were evaluated. Clinical response such as reduction in oxygen requirement and vasopressor utilization before and after treatment were examined.
Results: The rate of RT - PCR positive results were statistical significantly higher in pregnant women (p=0.003). The median WBC, lymphocyte and leukocyte values of the pregnant patients were higher (p=0.038, p=0.006 and p=0.035, respectively). The median hemoglobin, LDH and ferritin values of pregnant women were lower than those of non-pregnant individuals (p=0.032, p<0.001 and p=0.010, respectively). Mortality has been observed wit a rate of 17.5% in second trimester and 15% in the third trimester while 22.5% of women in the second trimester and 45% of women in the third trimester have survived COVID-19 infection.
Conclusion: Regarding the results of this study, we have observed differences in WBC, lymphocyte and leukocyte, median hemoglobin, LDH and ferritin values of pregnant women and non-pregnant individuals. Additionally, mortality rate was also comparable.

Keywords : COVID-19, pregnancy, mortality, D-dimer

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Article available in :
Volume 4, Issue 4, 2023
Page : 263-269
https://doi.org/10.47582/jompac.1313415
Article Information
Received : 12 Haz 2023
Accepted : 01 Tem 2023
Published : 30 Ağu 2023
Corresponding Author :

Emine Nilgün Zengin: Department of Anesthesiology and Reanimation, Ankara Bilkent City Hospital, Ankara, Turkiye

[email protected]
Citation : Seğmen F, Uysal E, Kılıçarslan G, Erdem D, Zengin EN. The clinical course of COVID-19 in pregnant and non-pregnant women. J Med Palliat Care. 2023;4(4):263-269.

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