Journal of Medicine and Palliative Care (JOMPAC) is an open access scientific journal with independent, unbiased, and double-blind review under international guidelines. The purpose of JOMPAC is to contribute to the literature by publishing articles on health sciences and medicine.

EndNote Style
Case Report
Scrotal pain related to terlipressin in the patient with hepatorenal syndrome
Hepatorenal syndrome is a table of kidney failure seen in patients with chronic liver parenchymal disease accompanied by refractory ascites. Vasoconstrictors are given in their treatment. Treatment-related ischemic complications are frequently observed, but ischemic scrotal pain has not been reported. In our case, a patient with chronic liver parenchymal disease due to chronic hepatitis B and who developed hepatorenal syndrome was presented. Scrotal pain and hyperemia of scrotal skin have appeared after the given terlipressin to the patient for hepatorenal syndrome. Treatment was discontinued due to considering an ischemic complication of terlipressin. Scrotal necrosis related to vasoconstrictor therapy has been previously reported. These complications usually occur after the 24th hour of treatment. The development of ischemic findings at the first hour of the treatment has prevented possible necrosis in our case.

1. Betrosian AP, Agarwal B, Douzinas EE. Acute renal dysfunction in liver diseases. World J Gastroenterol 2007 Nov 14; 13: 5552-9.
2. Arroyo V, Gines P, Gerbes AL, et al. Definition and diagnostic criteria of refractory ascites and hepatorenal syndrome in cirrhosis. International Ascites Club. Hepatology 1996; 23: 164-76.
3. Schrier RW, Arroyo V, Bernardi M, et al. Peripheral arterial vasodilation hypothesis: A proposal for the initiation of renal sodium and water retention in cirrhosis. Hepatology 1988; 8: 1151– 7.
4. Arroyo V, Clària J, Saló J, et al. Antidiuretic hormone and the pathogenesis of water retention in cirrhosis with ascites. Semin Liver Dis 1994; 14: 44– 58.
5. Akil ipek, Kasırga Erhun. Hepatorenal sendrom. Erciyes Tıp Derg (Erciyes Med J) 2004; 26: 132-40.
6. Lenz K, Hortnagl H, Druml W , et al. Ornipressin in the treatment of functional renal failure in decompensated liver cirrhosis. Effects on renal hemodynamics and atrial natriuretic factor. Gastroenterology 1991; 101: 1060-7.
7. Rose BD, Runyon BA. Diagnosis and treatment of hepatorenal syndrome. Up To Date 2007.
8. Akriviadis E, Botla R, Briggs W, Han S, Reynolds T, Shakil O. Pentoxifylline improves short-term survival in severe acute alcoholic hepatitis: A double-blind, placebo-controlled trial. Gastroenterology 2000; 119: 1637-48.
Volume 1, Issue 1, 2020
Page : 10-11